Apoptosis Reagents and Kits
Cayman Chemical Caspase-37 InhIbItr I 5mg
A non-nucleoside DNA methyltransferase inhibitor (IC50 115 nM in vitro) that significantly reduces the methylation of genomic DNA in cells at 10 M without detectable toxicity
Cayman Chemical Ac-VEID-AMCamonIum acetate 1mg
A potent selective chemical probe for the methyl lysine reading function of L3MBTL3 (Kd 120 nM IC50 40 nM) that competitively displaces mono- or dimethyl-lysine containing peptides
Cayman Chemical Caspase-1 Enzymehumnreco 20uL
An inactive derivative of PS-48 has been used as a negative control for the kinase activity of PDK1
Cayman Chemical Cel-Based asy Hoechst Dye 50uL
A dual peptide GCGR and GLP-1R agonist induces cAMP production in BHK-21 cells expressing human GCGR or GLP-1R (EC50s 1.83 and 0.92 pM respectively) reduces body weight and cumulative food intake in a mouse model of diet-induced obesity from 3-5 nmol/kg reduces body weight hepatic fat accumulation and fibrosis and plasma ALT levels in a mouse model of NASH induced by a high-fat high-fructose and high-cholesterol diet
Cayman Chemical Caspase-4 Enzymehumnreco 50uL
An inactive derivative of PS-48 has been used as a negative control for the kinase activity of PDK1
Cayman Chemical Caspase asy Buffer5X 5mL
A TRPV2 inhibitor (IC50 0.46 UM) selectively inhibits 2-APB-induced currents in a patch-clamp assay using HEK293T cells overexpressing TRPV2 at 0.3 or 1 UM over HEK293T cells overexpressing TRPV1 or TRPV3 at 3 or 10 UM reduces LPA-induced migration in PC-3M prostate cancer cells at 20 UM reduces LPA-induced increases in current in a patch-clamp assay using HEK293T cells
Sigma Aldrich Fine Chemicals Biosciences Annexin V-fITC Apoptosis D
Annexin V-fITC kit allows fluorescent detection of annexin V bound to apoptotic cells and quantitative determination by flow cytometry. The AnnexinV-fITC kit uses annexin V conjugated with fluorescein isothiocyante (fITC) to label phosphatidylserine sites on the membrane surface. The kit includes propidium iodide (PI) to label the cellular DNA in necrotic cells where the cell membrane has been totally compromised. This combination allows the differentiation among early apoptotic cells (annexin V positive PI negative) necrotic cells (annexin V positive PI positive) and viable cells (annexin V negative PI negative).
Sigma Aldrich Fine Chemicals Biosciences Mouse Tumor Necrosis facto
Tumor Necrosis factor (TNf ) is a proinflammatory cytokine. It is a transmembrane protein and the final protein is devoid of the extracellular domain. TNf -converting enzyme (TACE) catalyzes the formation of the soluble homotrimer TNf .
Cayman Chemical Hoechst 33342hydrochlorIde 5mL
A guanidine-modified biotin derivative and an inhibitor of iNOS and nNOS (Kis 21.8 and 37.5 UM for the mouse and rat enzymes respectively) prevents hypoxia-ischemia-induced decreases in brain phosphocreatine and ATP levels and increases in edema in the parietal cortex and striatum as well as reduces apoptosis in the parietal- and temporal cortex and striatum in piglets at 0.2 mg/kg every four hours increases survival of and decreases electrographic seizures in hypoxia-ischemia-injured piglets at 0.2 and 1 mg/kg every four hours LNPs containing 2-iminobiotin conjugated to poly-L-lysine have been used to improve LNP tumor targeting uptake and retention compared with LNPs containing biotin conjugated to poly-L-lysine in rats
Cayman Chemical Caspase-9 InhIbItr IIItrIf 1mg
An analytical reference standard that is structurally similar to known synthetic CBs intended for research and forensic applications
Cayman Chemical BIotIn-VAD-FMK 1mg
An isomer of guanine found naturally but also formed through oxidative damage to DNA mutagenic in mammalian and bacterial cells in vitro
Cayman Chemical Caspase-3 InhIbItr VII 5mg
An analog of FTY720 that is a competitive antagonist of S1P1 has a Ki value of 0 69 UM when assessed by SEW2871-induced activation of S1P1
Biolegend PerCP/Cyanine5.5 Annexin V
PerCP/Cyanine5.5 Annexin V Reactivity: All mammalian species; Apps: FC; Size: 100 tests